tert-butyl (R)-(pyrrolidin-2-ylmethyl)carbamate
tert-butyl [(2R)-pyrrolidin-2-ylmethyl]carbamate
CAS: 719999-54-9
Molecular Formula: C10H20N2O2
tert-butyl (R)-(pyrrolidin-2-ylmethyl)carbamate - Names and Identifiers
tert-butyl (R)-(pyrrolidin-2-ylmethyl)carbamate - Physico-chemical Properties
| Molecular Formula | C10H20N2O2 |
| Molar Mass | 200.28 |
| Density | 0.997 |
| Boling Point | 303.9±15.0 °C(Predicted) |
| Flash Point | 137.6°C |
| Vapor Presure | 0.000902mmHg at 25°C |
| pKa | 12.58±0.46(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.46 |
tert-butyl (R)-(pyrrolidin-2-ylmethyl)carbamate - Risk and Safety
| UN IDs | UN3077 |
tert-butyl (R)-(pyrrolidin-2-ylmethyl)carbamate - Introduction
tert-butyl [(2R)-pyrrolidin-2-ylmethyl]carbamate is an organic compound with the chemical formula C12H22N2O2. It is a white crystalline solid with a low melting point and melting point. tert-butyl [(2R)-pyrrolidin-2-ylmethyl]carbamate is a protecting group compound, which is widely used in multi-step reactions in organic synthesis.
tert-butyl [(2R)-pyrrolidin-2-ylmethyl]carbamate is mainly used as an amino protecting group, which can effectively protect the selectivity of the amino group reaction and control the reaction in the solution phase. It can be used in the synthesis of bioactive molecules, drug synthesis and peptide synthesis and other fields.
The method of preparing tert-butyl [(2R)-pyrrolidin-2-ylmethyl]carbamate is generally obtained by reacting BOC-aminomethylpyrrolidine with bromoacetone with a chiral catalyst. During the preparation process, attention should be paid to the control of reaction conditions to ensure the purity and yield of the product.
For safety information, tert-butyl [(2R)-pyrrolidin-2-ylmethyl]carbamate is stable under normal operating conditions, contact with strong oxidizing agents and moisture should be avoided. When in use, wear appropriate personal protective equipment and operate in a well-ventilated area to avoid harmful gases and vapors. In addition, the compound should be stored and handled properly to avoid mixing with flammable materials and organic compounds, and away from fire and high temperature environments. When handling this compound, the relevant safety practices should be observed.
tert-butyl [(2R)-pyrrolidin-2-ylmethyl]carbamate is mainly used as an amino protecting group, which can effectively protect the selectivity of the amino group reaction and control the reaction in the solution phase. It can be used in the synthesis of bioactive molecules, drug synthesis and peptide synthesis and other fields.
The method of preparing tert-butyl [(2R)-pyrrolidin-2-ylmethyl]carbamate is generally obtained by reacting BOC-aminomethylpyrrolidine with bromoacetone with a chiral catalyst. During the preparation process, attention should be paid to the control of reaction conditions to ensure the purity and yield of the product.
For safety information, tert-butyl [(2R)-pyrrolidin-2-ylmethyl]carbamate is stable under normal operating conditions, contact with strong oxidizing agents and moisture should be avoided. When in use, wear appropriate personal protective equipment and operate in a well-ventilated area to avoid harmful gases and vapors. In addition, the compound should be stored and handled properly to avoid mixing with flammable materials and organic compounds, and away from fire and high temperature environments. When handling this compound, the relevant safety practices should be observed.
Last Update：2024-04-09 20:52:54
